WebMar 8, 2024 · d, Huh7 cells expressing a TMEM41B sgRNA pool (TMEM41B KO) or TMEM41B cDNA infected with pseudoparticles harboring the HCoV-229E spike (n = 6 … WebPROTEIN SUMMARY SECTION OVERVIEW RNA DATA ANTIBODY DATA. TMEM41B INFORMATION. Proteini. Full gene name according to HGNC. Transmembrane protein …
TMEM41B and VMP1 modulate cellular lipid and energy …
WebApr 11, 2024 · Autophagy is a highly conserved recycling process of eukaryotic cells that degrades protein aggregates or damaged organelles with the participation of autophagy-related proteins. Membrane bending is a key step in autophagosome membrane formation and nucleation. A variety of autophagy-related proteins (ATGs) are needed to sense and … WebGene view. The gene view histogram is a graphical view of mutations across TMEM41B. These mutations are displayed at the amino acid level across the full length of the gene by … section 7 police act
TMEM41B is a novel regulator of autophagy and lipid …
WebAug 8, 2024 · Transmembrane Protein 41B (TMEM41B) and Vacuole Membrane Protein 1 (VMP1) are two ER-associated lipid scramblases that play a role in autophagosome formation and cellular lipid metabolism. TMEM41B is also a recently validated host factor required by flaviviruses and coronaviruses. WebTMEM41B AA mutation p.? (Unknown) CDS mutation c.*483_*485del (Deletion) Nucleotides inserted n/a Genomic coordinates GRCh38, 11:9282940..9282942, view Ensembl contig CDD NP_055827.1 HomoloGene 42740, view the multiple sequence alignment Ever confirmed somatic? Yes Remark n/a Recurrent n/a Drug resistance WebJun 7, 2024 · TMEM41B and VMP1 are integral membrane proteins of the endoplasmic reticulum (ER) and regulate the formation of autophagosomes, lipid droplets (LDs), and lipoproteins. Recently, TMEM41B was identified as a crucial host factor for infection by all coronaviruses and flaviviruses. section 7 playoffs