Rkip and yy1 international symposium

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August undefined, 2024

WebJan 31, 2014 · The presence of a dysregulated NF-κB/Snail/YY1/RKIP loop was recently established in metastatic prostate cancer cells and non-Hodgkin’s lymphoma; however, its involvement in multiple myeloma (MM) has yet to be investigated. Aim of the study was to investigate the role of the NF-κB/Snail/YY1/RKIP circuitry in MM and how each gene is … WebDec 11, 2024 · Of interest, a follow up of these contributions above can be followed in a forthcoming International Conference titled “ Prognostic and Therapeutic Implications of …

Gene set enrichment analysis of the NF-κB/Snail/YY1/RKIP

WebWe evaluated the RKIP and pRKIP protein by immunohistochemistry in control skin, pigmented nevi and melanomas, and through Western blotting in human normal melanocytes and in four different ... WebWelcome to the RKIP and YY1 Symposium 2024 in Catania, Sicily (Italy) Dear Colleagues, It is our great pleasure to invite you to join the 1st Joint International Symposium on … chord em7 sus for guitar

Therapeutic targeting of SNAIL, RKIP, and YY1 in tumor …

WebMay 5, 2024 · The human RKIP gene is located on chromosome 12q24 and contains a promoter region with several sequences involved in the regulation of RKIP transcription, such as the E1-Box, E2-Box, CpG islands, and androgen-response elements (ARE) [21,22,23].Like many proteins, RKIP can undergo post-translational phosphorylation … WebChiefly, these findings suggest that targeted inhibition of YY1 by specific small molecule inhibitors and/or the specific induction of RKIP expression and activity are potential … WebThis review discusses the molecular regulation of EMT in cancer cells through the activity of the dysregulated NF-κB/Snail/ YY1/PTEN/RKIP circuitry. In addition, we propose YY1 as a potential novel prognostic biomarker for EMT and a therapeutic target for both the prevention of metastasis and the reversal of resistance. chor der geretteten nelly sachs analyse

Nitric Oxide (NO) induced sensitization of tumor cells to TRAIL ...

[PDF] RKIP: A Key Regulator in Tumor Metastasis Initiation and ...

WebJul 29, 2024 · The ‘International Symposium on Managing Land and Water for Climate-Smart Agriculture’ aims to facilitate the exchange of information and knowledge among soil, water and environment professionals from developed and developing countries to advance the understanding, collaboration and capabilities to respond to the impact of climate … WebMarch 8-11, 2024 - RKIP and YY1 Symposium 2024. March 8-11, 2024 - RKIP and YY1 Symposium 2024. Registration form deadline: January 31st, 2024. First Name * Last … chord epic twin test chord everybody change

"WebYY1’s negative regulation of RKIP and vice versa. In these roads, YY1 represents the green traffic light (green lines) which promotes cancer properties, including tumor spreading and resistance to therapy, whereas RKIP acts as the red traffic light (red lines) that stops tumor functions. Accordingly, the YY1/RKIP motif may serve as a potent ... " - Rkip and yy1 international symposium

Rkip and yy1 international symposium

Prognostic and Therapeutic Applications of RKIP in Cancer

WebHis group has also highlighted the relationships of the NF-κB/Snail/YY1/RKIP circuitry with specific cancer-related gene sets in multiple myeloma (Tumour ... Baritaki co-organized … WebOn the same context, we have previously identified the critical role of YY1 as a mediator of tumor resistance to both chemo-and immunomediated apoptosis in various cancer …

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WebNov 22, 2024 · Raf kinase inhibitor protein (RKIP), an important modulator of intracellular signalling pathways, is commonly downregulated in multiple cancers. This reduction, or … WebApr 15, 2011 · Abstract. The Raf kinase inhibitory protein (RKIP) acts as an activator of apoptosis and inhibitor of metastasis in prostate cancer. Diminished expression of RKIP has been reported in several cancers including prostate carcinomas; however, the underlying mechanism of RKIP regulation remains largely unknown. RKIP transcription is inhibited by …

WebRKIP mechanistically modulates the apoptotic regulators of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) signaling. Because of its critical role in human cancers, … WebIn 2024, Dr. Stavroula Baritaki, organised the second RKIP workshop in Crete during which we discovered the necessity of creating an international consortium to deal with the …

WebFeb 3, 2024 · Description. Prognostic and Therapeutic Applications of RKIP in Cancer provides updated reviews on the chemistry, signaling, pre-clinical and clinical activities, and role of RKIP expression levels for diagnostics, prognosis and potential interventions. The development of novel compounds and conjugates that selectively induce RKIP expression … WebJan 1, 2024 · The RKIP/Raf interaction is regulated by RKIP phosphorylation at Ser-153 as well as occupancy of the ligand binding domain of RKIP by a phospholipid or other ligands …

WebJan 31, 2014 · The present study highlights the relationships of the NF-κB/Snail/YY1/RKIP circuitry genes with specific cancer-related gene sets in multiple myeloma. The presence of a dysregulated NF-κB/Snail/YY1/RKIP loop was recently established in metastatic prostate cancer cells and non-Hodgkin’s lymphoma; however, its involvement in multiple myeloma …

WebResurrection plants can survive prolonged life without water (anhydrobiosis) in regions with seasonal drying. This desiccation tolerance requires the coordination of numerous cellular processes across space and time, and individual plant tissues face unique constraints related to their function. chordettes singing groupWeb1st Joint International Symposium PROGNOSTIC AND THERAPEUTIC IMPLICATIONS OF RKIP AND YY1 IN CANCER, DIABETES AND CARDIOVASCULAR DISEASES March 11, 2024 … chord e on guitarWebThe transcription factor Yin Yang 1 (YY1) can favor several aspects of tumorigenesis. In turn, Raf-1 Kinase Inhibitor Protein (RKIP) inhibits the oncogenic activities of MAPK and NF-κB pathways and promotes drug-induced apoptosis. Mutual influences between YY1 and RKIP may exist, and there are alrea … chord energy corporation chrdWebNov 20, 2024 · Yin Yang 1 (YY1), a dual function transcription factor, is known to regulate transcriptional activation and repression of many genes associated with multiple cellular processes including cellular differentiation, DNA repair, autophagy, cell survival vs. apoptosis, and cell division. Owing to its role in processes that upon deregulation are … chordeleg joyeriasWebRKIP and YY1 2024 - International Conference - Catania: Biometec - Antonio Cantarella ... chord everything i wantedWebGSK3 and RKIP in metabolic disorders: A proposal for a joint international research program Fahd Al-Mulla. 9:25 am RKIP protects mitochondria under ischemic conditions Theresa … chord energy investor presentationWebJan 11, 2024 · YY1, discovered in the early 1990s by several groups using a variety of approaches 1-5 is a member of the GLI-Kruppel family of zinc finger DNA binding proteins that can activate or inactivate gene expression depending on partner proteins, promoter context and chromatin structure. 6 YY1 has activity that is dependent 6, 7 and … chord face to face