Para-aminohippurate (PAH) clearance is a method used in renal physiology to measure renal plasma flow, which is a measure of renal function. PAH is completely removed from blood that passes through the kidneys (PAH undergoes both glomerular filtration and tubular secretion), and therefore the rate at which the kidneys can clear PAH from the blood reflects total renal plasma flow. WebNet PAH secretion is restricted to PTC cell monolayers and is sensitive to inhibition by excess PAH. The data are expressed as the mean ± SEM of 4 monolayers per condition …
Excretion of para‐aminohippurate in the isolated perfused rat …
Webtubular secretion of organic anions as exemplified by the model organic anion PAH. The secretion of PAH consists of at least two steps, uptake from the blood across the … Web2. Countercurrent exchange occurs as both solutes and water move freely in and out of the . 3. The increase in filtrate osmolarity as it flows down the descending limb is due to … i have been trying not to go off the deep end
Hypoxia-inducible factor signaling in pulmonary hypertension
WebDespite the advent of new therapies and improved outcomes in patients with pulmonary arterial hypertension (PAH), it remains a life-shortening disease and the time to diagnosis … WebNet PAH secretion was observed at low perfusate free PAH concentrations. Net PAH transport was zero at a perfusate free PAH concentration of 2.1 mM. Above this level … WebJun 1, 2001 · A dependence of PAH accumulation, or of PAH secretion, on extracellular Na + and α-ketoglutarate was found in crab urinary bladder as well as in intact tubules of … is the kfc zinger burger spicy